Preparation, PhysicoChemical Studies and Antimicrobial Evaluation of 2-(2-[(2-hydroxyphenyl)ethanimidoyl]Phenyl-ethanimidoyl)phenol of Novel Transition metal Chelates

A series of chelates of Zr(IV), La(III) and Ce(IV) with a bidentate ligand, 2-(2-[(2- hydroxyphenyl)ethanimidoyl]phenylethanimidoyl)phenol were prepared and characterized on the basis of elemental analysis, molar conductivity, mass spectra, infrared, 1HNMR, TGA and UV-Visible spectra. Their molar conductance values indicated that all the chelates are non-electrolyte. From elemental analysis data, the chelates have been found to be 1:1 (metal: ligand). According to these data, an octahedral geometry was suggested for the chelates. The ligand and its metal chelates were screened for their physiological activities against some pathogenic antimicrobial activity two Gram-negative (Escherichia coli, Salmonella kentucky), two Gram-positive (Lactobacillus fermentum, Streptococcus faecails) bacterial strains and fungi unicellular (Fusarium solani) and filamentous fungi (Aspergillus niger). The activity data showed that the metal chelates have antibacterial and antifungal activity more than the parent Schiff base ligand against one or more bacterial or fungi species.