Confronting a Ganglioglioma: Case Report

Introduction Gangliogliomas are rare neuroepithelial tumours that account for only 0.4 % of the CNS tumours hence no prospective studies are done regarding the management. This case report describes management of ganglioglioma and use of radiotherapy in the adjuvant setting. Case Description An eight year old girl presented with complaints of seizures and after evaluation underwent craniotomy and decompression. Subsequently was considered for adjuvant radiotherapy as post-op histopathology revealed Anaplastic ganglioglioma grade 3. Post radiotherapy MRI whole brain scan at 9 months showed features of a porencephalic cyst in the treated area with enhancing wall and no significant solid component. A follow up MRI screening scan two years later showed mild decrease in the enhancement of the cyst wall and a neurosurgical opinion was taken where in the patient was advised to be on follow up. Conclusion Anaplastic gangliogliomas are aggressive tumours which despite being dealt with surgery and radiotherapy have a propensity to recur thereby reiterating the fact of needing an insistent adjuvant therapy which has to be determined in future studies as the definitive treatment options for this tumour have not been elaborated as the tumour is very rare.