Body Temperature Trends and Fever Risk in the Parasitaemia of Plasmodium Falciparum Treated Children at Lake-Alau, Borno State, North Eastern Nigeria

The aim of this study is to assess the relationship between body temperature patterns and fever ( 37.50C) risks in the parasitaemia of uncomplicated Plasmodium falciparum malaria in children (59 months). The ever increasing resistance to monotherapies informed the assessment of the combination therapies of Artesunate+Sulphadoxine-Pyrimethamine (AT+SP) and Amodiaquine+ Sulphadoxine-Pyrimethamine (AQ+SP) at the malaria endemic settlements of Lake-alau, Borno State, and North- Eastern Nigeria. The result shows a response of parasitaemia to body temperatures was 55.77 % in AT+SP treated children compared to higher response of 64.29 % by AQ+SP patients. Similarly, the slope of regression showed a temperature clearance of 0.2071 0C for AT+SP in contrast to 0.1714 0C for AQ+SP which relates for each l of depleted blood parasites there was a higher temperature relief in AT+SP than AQ+SP patients having a mean marginal difference of 0.0357 0C between the two respective drug groups. In a similar vein, the proportion fever risk was higher (55.75 %) in AQ+SP treated children compared to AT+SP (50.69 %). Conversely, the rate of fever clearance due to the percentage of each parasite cleared was 12.243 % compared to 12.643 % for the two respective drugs, with mean terminal parasite clearance of 99.86 % and 99.7 %, respectively.