A CLINICAL CASE OF PROGRESSIVE COURSE OF SARCOIDOSIS OF THE RESPIRATORY ORGANS

Sarcoidosis is a systemic inflammatory disease of unknown etiology, characterized by the formation of noncaseating granulomas and multiple system organ damage. Sarcoidosis therapy is aimed at prevention and reducing inflammation as well as improving patient's symptoms and quality of life. Active observation is preferred for patients with morphologically confirmed diagnosis in the absence of a lifethreatening condition, organ and system dysfunction as well as disease progression. Alternative therapy may include alphatocopherol and/or pentoxifylline. Treatment with glucocorticosteroids is used for a long period of time (12-24 months) only when clinically indicated. The presented clinical case of progressive course of respiratory organ sarcoidosis is intended to draw the attention of doctors to the peculiarities of examination, treatment and observation of such patients. The case is discussed from the perspective of personalized medicine and modern clinical guidelines.