Preeclampsia and Intra-Abdominal Hypertension

Preeclampsia is an important obstetric disorder. This disease becomes an important problem for many pregnant women and it can result in severe clinical problems including to death. Marshalov et al. reported their interesting findings and proposed that “The results of our research present the first multi-factorial model of preeclampsia etiology, where the trigger mechanism is the abdominal hypertension syndrome [1].” In fact, the exact etiology of preeclampsia is still unknown and it is believed to be a multifactorial disease. The underlying vascular problem is usually mentioned as important factor [2]. The hypothesis on the intra-abdominal hypertension induced preeclampsia is a new hypothesis proposed by Sawchuck et al., [3]. This concept is based on the basic physical mechanics on the pressure rule [3]. The intra-abdominal hypertension can be expected in any pregnant women who have significantly changes of abdominal cavity due to increasing size of uterus when the gestational age of the fetus increases. If we apply the concept of management of the intraabdominal hypertension, relieving of the pressure, which is the important factor causing organ failure, should be urgently done [4]. This concept is concordant with classical gynecological principle for management of severe preeclampsia and eclampsia by termination of pregnancy. An “applied negative abdominal pressure device” is also proposed for management of preeclampsia [5].