To Study the Efficacy of Primary Pterygium Excision Surgery with Conjunctival Limbal Autograft using Autologous Blood and with Fibrin Glue

Purpose: To study the efficacy of autologous blood and compare the results with fibrin glue in primary pterygium excision surgery using conjunctival limbal autograft technique. Methods: Prospective, Randomised, interventional, hospital based, comparative study. Sixty eyes of sixty consecutive patients coming to ophthalmology OPD of our tertiary care centre with primary progressive pterygium were selected. Each patient with primary progressive pterygium were randomly assigned to group A and B and were operated. Group A includes 30 patients with conjunctival limbal autograft using autologous blood technique and Group B includes 30 patients with pteryguim excision with conjunctival limbal autografting using fibrin glue. The patients were followed up postoperatively on days 1, 7 and then at months 1, 6, 12 and 18. The main outcome measures included were graft adherence, recurrence rate and postoperative complications. Results: By the end of 18 months follow up, the recurrence rate was 3.33% in fibrin blood group (Group - B) and no recurrence in conjunctival limbal autograft group using Autologous blood (Group - A). There were no severe vision threatening complications in either group. Conclusion: Both the methods of conjunctival limbal autografting using autologous blood and fibrin glue were found to be equally effective and safe in terms of graft adherance and post operative complications. The recurrence rate in autologous blood technique were statistically not significant.