Incidence of Contrast Agent Induced Acute Kidney Injury and Analysis of Factors affecting it

Contrast agents are widely used in many radiological investigations. Contrast induced acute kidney injury (CIAKI) is the third most common cause of hospital acquired renal insufficiency. The aims of this study were to assess the incidence of CIAKI and to analyse effects of various factors affecting CIAKI. The presence and severity of acute kidney injury was compared between a group of patients exposed to contrast agent to that in a group of patients not exposed to contrast agent. and the effect of various factors affecting it was noted. There was a statistically significant difference in the rise of S Cr in the exposed group as compared to the non exposed group. The incidence rate of CIAKI was 10.9%. Patients with low eGFR (?60 ml/min/1.73 m2) had a 17.9 times chance of being affected by CIAKI as compared to patients with eGFRgreater than60 ml/min/1.73m2 and diabetics had a 7.6 times higher chance of getting affected by CIAKI as compared to non diabetics. Contrast administration can lead to rise in S Cr and thus acute kidney injury in a small but significant number of patients. Low eGFR and diabetes are associated with development of CIAKI.