Oxidative Stress in Diabetic Obese Patients Attending Selected Tertiary Hospital in Abia State Nigeria
Journal: International Journal of Trend in Scientific Research and Development (Vol.5, No. 6)Publication Date: 2021-10-01
Authors : Egejuru O. Leonard Akubugwo I. Emmanuel Chinyere O. Godwin Ugorji N. Beatrice;
Page : 1325-1331
Keywords : Anti-Oxidant defense system; Superoxide dismutase; obesity; Malondialdehyde;
Abstract
Oxidative stress has continued to play major roles in the etiology of many metabolic diseases, diabetes and obesity inclusive. The study on oxidative stress in diabetic obese patients was carried out with patients from two tertiary hospitals in Abia State Nigeria who gave their consent to participate in the study. A total of 120 patients 18 years and above who were stratified into five different age groups were enrolled for the study. Following approved protocols fasting blood samples were collected and a semi structured questionnaire used to collect other data needed for the study. Data was analyzed using T test and SPSS version 20.0 software and result considered significant at p 0.05. The results showed that body mass index BMI were higher in females than males 37.20 vs 35.12 kg m2. The oxidative stress markers or parameters of the experimental groups follow a uniform trend of significant increases in Malondialdehyde MDA , and significant decreases in enzymes Glutathione peroxidases GPx and Superoxide dismutase SOD and vitamins C and E . Also middle aged patients 30 50 years were equally affected with diabetes and more in females than males. Generally increased oxidative stress or impaired antioxidant defense system in diabetic obese condition may contribute to increased metabolic damage. Egejuru O. Leonard | Akubugwo I. Emmanuel | Chinyere O. Godwin | Ugorji N. Beatrice "Oxidative Stress in Diabetic-Obese Patients Attending Selected Tertiary Hospital in Abia State Nigeria" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-5 | Issue-6 , October 2021, URL: https://www.ijtsrd.com/papers/ijtsrd47548.pdf Paper URL : https://www.ijtsrd.com/biological-science/biochemistry/47548/oxidative-stress-in-diabeticobese-patients-attending-selected-tertiary-hospital-in-abia-state-nigeria/egejuru-o-leonard
Other Latest Articles
- Field Controlled Picker Robot
- Revised Right Hand Grip Rule for an AC DC Current
- Socio Economic Stages and Development of Business Activity
- Role of Diet and Lifestyle Modification in the Prevention of Cardiovascular Disease A Review Study
- Teaching the Uzbek Language is a Topical Issue On the Example of an Interactive Model of Education
Last modified: 2022-02-28 19:50:53