ASSOCIATION BETWEEN CHRONIC PERIODONTITIS AND SERUM LIPID LEVELS – A CROSS SECTIONAL STUDY

Objectives: Periodontal disease is a chronic inflammatory disease inducing marked changes in the plasma concentrations of cytokines leading to a catabolic state characterized by altered lipid metabolism and hypertriglyceridemia. The main objective of the present study was to evaluate the effect of periodontal infection on serum levels of triglycerides (TGL), total cholesterol (TC), high‑density lipoprotein (HDL) cholesterol, and low‑density lipoprotein (LDL) cholesterol. Materials and Methods: A sample of 100 subjects; 50 chronic periodontitis cases and 50 periodontally healthy individuals with an age range of 25 to 55 years were included in the study. Periodontal parameters including Plaque Index, Gingival Index, Probing Depth, and Clinical Attachment Level were recorded. Venous blood samples were obtained after 12 hours fasting period from antecubital vein and serum levels of TGL, TC, HDL, and LDL cholesterol were measured. Results: The levels of TGL, TC were significantly higher for periodontitis group (P<0.05) as compared to the periodontally healthy group. HDL cholesterol levels were significantly lower in periodontitis group (P<0.05) as compared to the periodontally healthy group.