Synthesis of a New Copoly 1,3,4-Oxadiazole from Copoly Imine with Iodine and Study of Their Biological Activity
Journal: Chemical Methodologies (Vol.6, No. 6)Publication Date: 2022-06-01
Authors : Israa Sattar Gatea; Entesar. O. Al-Tamimi;
Page : 446-456
Keywords : copoly Schiff bases; Copoly 1; 3.4-oxadiazole; Biological activity;
Abstract
Synthesis of a new series of poly (N-substituted-maleimide-co-2,5- substituted-1,3.4-oxadiazole) was carried out. The first step includes preparation of copoly imine by reaction of different aldehydes with copoly acid hydrazide (1-15). The second step indicated the reaction of copoly imine with iodine in the presence of K2CO3 to give poly (N-substituted-maleimide-co-2,5-substituted-1,3.4-oxadiazole). All prepared compounds were characterized by softening points, FT-IR, and some of them by 1H-NMR and TGA, and then their Biological application was studied and some of the physical properties.
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