CAUSE, EPIDEMIOLOGY, MODE OF TRANSMISSION AND MANAGEMENT OF COVID-19

Corona virus is a pandemic disease according to WHO (World health organisation). COVID-19 is caused by acute respiratory syndrome coronaviruse2 (SARAS-CoV-2). Initially, COVID-19 was started in Wuhan, a central china in December, 2019. The CFR (case fatility rate) depend upon the availibity of health care, age and health problem with in the population. On 12 January 2020, the World Health Organization temporarily named the new virus as 2019 novel corona virus (2019‐nCoV). The sporadic outbreaks of new types of CoVs remind us that CoVs are severe threat to affect the global public health. According to WHO, 87,137 cases was confirmed across worldwide since the beginning of the epidemic. Out of these, 2977 (3.42%) have been fatal. About 92% (79,968) of the confirmed cases were recorded in China, where almost all the deaths were also recorded (2,873, 96.5%) It is highly likely that new CoVID outbreaks are unavoidable in the future due to changes of the climate, ecology and increased interactions of human with animals. Thus, there is an urgent need to develop effective therapies and vaccines against COVID-19. At present, there is no vaccine or antiviral treatment for human corona virus, so that identifying the drug treatment options as soon as possible is critical for the response to the 2019-nCoV outbreak.