ResearchBib Share Your Research, Maximize Your Social Impacts
Sign for Notice Everyday Sign up >> Login

THE MITOCHONDRIAL SUGAR DISEASE AND MOLECULAR MECHANISM

Journal: International Education and Research Journal (Vol.6, No. 3)

Publication Date:

Authors : ;

Page : 44-48

Keywords : Diabetes and deafness (DAD); Sensorineural hearing loss.Cardiomyopathy; Adenosine deaminase; Glucokinase gene in type 2 diabetes mellitus;

Source : Downloadexternal Find it from : Google Scholarexternal

Abstract

Mitochondria are the power factories of the cells and produce ATP by oxidizing reducing equivalents via the respiratory chain. These reducing equivalents originate mainly from the citric acid cycle that also occurs within the mitochondria. Human mitochondria contain their own genetic material in the form of circular DNA that encodes for only a fraction of the mitochondrial components. The other mitochondrial components are nuclear encoded. Furthermore, the respiratory chain and mitochondrionassociated monoamine oxidase are major producers of reactive oxygen radicals. As a result, mutations in mtDNA can deregulate multiple processes within cells and the balance of this deregulation may contribute to the clinical phenotype Mitochondrial diabetes affects up t

Last modified: 2022-04-26 18:53:24