Corticosteroid in Dengue Hemorrhagic Fever as Preventive Treatment of Severe Outcome: A Case Report

Dengue is known as the most common vector-borne viral infection between humans by Aedes genusmosquito. Dengue has a broad spectrum of disease, ranging from asymptomatic infection to a severe systemic plasma leakage syndrome. Pathogenesis of severe dengue stillpoorly understood, one factor that is thought to cause the dreaded shock syndrome is antibody-dependent enhancement. Despite of fluid replacement therapy as the main treatment, corticosteroids usage in order to suppress immune-mediated mechanisms in DHF also expected to prevent severe outcome. Since this is still controversial, further research is still very much needed.