Assessment of Functional Group in Herbal Formulation Thalisapaththiri Choornam through Fourier Transform Infrared Spectroscopy

Siddha medical practice originated from time immemorial and developed gradually to an longer extent. Pharmacological evaluation of these plants and their taxonomical relatives leads to development of invaluable drugs for dreaded diseases. Hepatocytes (hepar =liver + cyte = cell) are responsible for making many of the proteins in the body that are required for many functions. The siddha formulation ?Thalisapathithiri chooranam? is used .The functional groups of this formulation are analysed through FTIR Spectrocopy and the biological roles of the functional groups are discussed in this paper. To explore the elemental characterization of herbal Thalisapaththiri choornam.The ingredients used in the trial drug are Elam (Eletteria cardamomum), Sathikkai (Myristica fragrans, Vaalmilagu (Piper cubeba), Vaividagam (Embelia ribes),Chirakam (Cuminum cyminum), Kottam (Costus speciosus), Nellivatral (Dry alma roots), Sombu (Foeniculum vulgare) Karampu (Syzygium aromaticum), Chatipaththiri (Myrstica fragrens), Lavangapattai (Cinnamomumverum), Thaniya (Coriandrum sativum), Thippili (Piper longum), Akarkara (Anacyclus pyrethrum), Thandrikai(Terminalia bellerica)Jadamanji (Nardostachys grandiflora), Thalisapaththiri (Abies spectabilies),Sugar (Saccharum officinarum).The trial drug is prepared as per siddha literature kannuswaamy paramparai vaithiyam pg no. 105. The Functional Group studied through FTIR study. It can be correlated in WHO recommended parameters for confirmed the standardizations in above drug. FTIR Characterization of trial drug "Thalisapaththiri choornam" shows the presence of some functional group such as alkenes, Nitrocompound, Aromatic compounds, Carboxylic acid, alkyl aryl ether, phosphorus,alcohol amine salt, silicon function and Halo compounds. This study forms the base for the pharmaceutical analysis of "Thalisapaththiri choornam" which will be followed by safety and efficacy studies later. All the modern scientific parameters provide it is minimal size particles and good characteristic nature of the drug. Thae characterized functional groups are analysed throughresearch papers from journals which provide the information that they have hepatoproctetive, antioxidant, hypolipidemic, Immunomodulator, antimicrobial, antiviral, cytotoxic activities .So Thalisapaththiri choornam is highly therapeutic in Jaundice as mentioned in siddha text books.