Metabolomics approach for discovering disease biomarkers and understanding metabolic pathway
Journal: Journal of Analytical Science and Technology (JAST) (Vol.2, No. 3)Publication Date: 2011-12-15
Authors : Jeeyoun Jung Zihey Jang Geum-Sook Hwang;
Page : A189-A193
Keywords : metabolomics; biomarker; metabolic pathway; NMR;
Abstract
Metabolomics, the multi-targeted analysis of endogenous metabolites from biological samples, can be efficiently applied to screen disease biomarkers and investigate pathophysiological processes. Metabolites change rapidly in response to physiological perturbations, making them the closest link to disease phenotypes. This study explored the role of metabolomics in gaining mechanistic insight into disease processes and in searching for novel biomarkers of human diseases.
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Last modified: 2012-11-07 23:18:15