Effect of Serum Magnesium Level on Short Term Outcome of Different Types of Acute Stroke in a Tertiary Level Hospital in Bangladesh

Background: Magnesium (Mg2+) has shown to have important effect in vascular system, and thought to be a risk factor for ischemic stroke and linked the outcome of intracerebral hemorrhage. However, very limited evidence was sought particularly in our country perspective. Methods: This hospital based cross-sectional study was conducted at the Department of Medicine in Dhaka Medical College Hospital, for a period of 6 months from October 2018 to March 2019. Patients with acute stroke were included into the study after confirmation of the diagnosis and matching other selection criteria. Written informed consents were taken from the all study subjects and ethical issues were ensured. Data were collected by interview using a semi-structured questionnaire. Short term outcome assessment was done by Modified Rankin Scale (MRS). Results: Among 100 patients, 58% were males and 42% were females. Mean age was 60.46 (?10.14 SD) years and prevalent (48%) age group 61-70 years. Of all, 42% were diagnosed as ischemic stroke, 40%-intracerebral haemorrhage and 18% were subarachnoid hemorrhage. Hypomagnesemia was present in 59.5% of ischemic stroke patients whereas it was present in 12.5% and11.1% cases in hemorrhagic stroke and SAH patients, respectively. Serum magnesium level was significantly lower in ischemic stroke patients in comparison to patients with hemorrhagic stroke and SAH (pless than0.001). This hypomagnesemia is related to poor short term outcome in ischemic stroke patients (pless than0.05), but not significantly in patients with hemorrhagic stroke and SAH. Conclusion: Hypomagnesemia is more prevalent in ischemic stroke patients than other type of stroke and this lower level of hypomagnesemia also has impact on short-term outcome in ischemic stroke patients.