Management of Periodontal Intrabony Defect Using Sticky Bone and GTR Membrane: A Case Report

Background: Periodontal regeneration in particular represents regain of lost periodontal tissues either by regenerative techniques to be used alone or in combination with an adjunct. Platelet-rich Fibrin (PRF) is an autologous product that is derived from whole blood by applying the process of gradient density centrifugation. Use of platelet concentrates is promising due to its autologous nature, release of multiple growth factors, low cost, ease of procurement and comfortable handling. Injectable PRF (i-PRF) can be combined with bone grafts to form sticky bone with superior handling and healing properties. Hereby, we report a case with intra bony defects treated with sticky bone and barrier membrane with a 1-year follow-up. Methodology: 10 ml of the patient?s venous blood was collected and i-PRF was obtained by low centrifugation protocol. Sticky bone was prepared by mixing i-PRF with alloplast and was placed in intrabony defect. A bioresorbable collagen membrane was placed over the sticky bone followed by periodontal flap closure. Results: A reduction in the Probing pocket depth (PPD) from 7mm (Pre-operative) to 3mm, Clinical attachment loss (CAL) from 8mm to 4mm. Conclusion: Significant improvement in clinical parameters such as PPD, CAL and radiographic bone fill indicates success of regenerative therapy using i-PRF with bone grafts.