Histopathological Study of Gallbladder Disease in Tertiary Care Centre

Background: Disorder of gallbladder affect significant population in world. Gallbladder is affected by inflammation, infection, benign and malignant conditions. Most of are due to cholelithiasis where females are affected more than male. The present study aim to delineate the occurrence of various gallbladder histopathology. Aim: To study the histopathological lesions of gallbladder in cholecystectomy specimens. To determine the age and sex distribution among patients with lesions. Materials and Methods: A study was conducted from may 2021 to october 2021 in department of pathology. Total 200 cases of cholecystectomy specimens were preserved in 10% neutral buffered formalin, surgically dissected, processed, stained using hematoxylin & eosin stain and evaluated. Results: The most common histopathological diagnosis was chronic cholecystitis followed by acute cholecystitis. Female preponderance was observed in all gallbladder diseases. The present study carried out in our institution showed gall bladder malignancy was uncommon. Conclusions: Almost all cases of gallbladder lesions are inflammatory in origin and of which the most common cause causing diseases was chronic calculous cholecystitis. Malignancy is uncommon and presents late in the course with the nonspecific symptoms, which can misguide the clinicians. Diagnosis of malignancy was made only by Histopathological examinations.