Estimation of Asprosin Levels in Female Iraqi Patients with Type 2 Diabetes and Hypothyroidism
Journal: Journal of Medicinal and Chemical Sciences (Vol.6, No. 2)Publication Date: 2023-02-01
Authors : Nedaa A. Lefta; Ahmed Y. Abed; Baydaa A. Abed;
Page : 433-439
Keywords : Asprosin; glucose metabolism; insulin resistance; Hypothyroidism; Thyroid Dysfunction; lipid profile;
Abstract
Adipose tissue secretes the hormone asprosin. The asprosin molecule has several roles in the central nervous system and other body systems: hunger, glucose metabolism, insulin resistance (IR), and cellular death. IR is pathologically associated with high asprosin levels. Patients with type 2 diabetes mellitus (DMІІ) are more likely to have thyroid problems. over time, many diabetics develop thyroid dysfunctional symptoms. the study included 80 women. forty had hypothyroidism with diabetes (DMII), and 40 were healthy controls. gathered samples from the National Diabetes Center, Al-Mustansiriyah University (Iraq), and College of Science for Women/University of Baghdad/Iraq, 35 to 65-year-olds. Dec. 2021-March 2022. the findings of this study indicate that asprosin, FBG, BMI, TSH, cholesterol, triglyceride, VLDL, and LDL concentrations increased significantly when compared to the healthy group. additionally, there was a real decrease in T3 and HDL levels when compared to the healthy group. Whiles The T4 level, however, did not show any statistically significant variations. Hypothyroidism and DMIІ patients showed high serum asprosin, which is linked with poor glycemic and lipid management. It's a biomarker for diabetes and thyroid issues.
Other Latest Articles
- COVID-19 Vaccine Hesitancy among Iraqi Dentists
- High-Performance Thin-Layer Chromatography Phytochemical Profiling, Antioxidant Activities, and Acute Toxicity of Leaves Extracts of Lannea velutina A. Rich
- The Role of Lipopolysaccharide in Initiation and Progression of Peri-implant Mucositis
- Synthesis, Identification, and Anti-oxidant Activity of Di-Organotin (IV)-Cephalexin Complexes
- Preparation, Characterization, and Ninhydrin Removal by Al2O3 and V2O5 Nanoparticles
Last modified: 2022-09-12 04:05:47