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Synthesis, Identification, and Anti-oxidant Activity of Di-Organotin (IV)-Cephalexin Complexes

Journal: Journal of Medicinal and Chemical Sciences (Vol.6, No. 2)

Publication Date:

Authors : ; ;

Page : 392-401

Keywords : Organotin(IV) complexes; Cephalexin; spectrum observations; Antioxidant activity; DPPHmethod;

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Abstract

Three organotin complexes were successfully synthesized via condensation reactions of cephalexin) ligand (and di-organotin (IV) complexes in the presence of sodium hydroxide. Infrared, nuclear magnetic resonance (1H, 13C, 119Sn NMR) and elemental analyses were used to characterize the produced compounds. Based on the spectrum observations octahedral geometry was proposed for the complexes synthesized. This study looked at the antioxidant activity of tin (IV) compounds using two methods free radical scavenging activity (DPPH) and the CUPRAC method. Dioganotin (IV)-cephalexin complexes showed higher antioxidant activity than ligands due to the metal moiety, while complex (Me2SnL2) showed higher antioxidant activity than other complexes.

Last modified: 2022-09-12 04:05:47