Newer Parameters on Electronic Cell Counter for Diagnosis of Infections

Blood stream infection (BSI) and sepsis are life threatening conditions and early identification of pathogen with prompt intervention is important for patient management. Need for early diagnosis of sepsis has incredibly boosted the research for innovative biomarkers. The cellular and morphological characterization of cells is an indispensable part of hematology workup. The automated hematology analyzers are being routinely used for total cell counts and differential leukocyte analysis. But technological advancements in automated hematology analyzers have paved the way for many additional parameters which are capable of providing extended information to help clinicians and laboratory professionals. This review emphasizes the application of additional innovative parameters reported by modern hematology analyzers as a tool for early recognition of sepsis with impact on clinical practice.