Synthesis, Characterization of Nickel (II) Phthalocynine, and Screening of Its Potential Antibacterial Activity
Journal: Journal of Medicinal and Chemical Sciences (Vol.5, No. 7)Publication Date: 2022-12-01
Authors : Osama S. Hashim;
Page : 1242-1246
Keywords : Nickel (II) Phthalocynine; UV-Visible; FTIR and HNMR spectroscopy;
Abstract
Nickel (II) Phthalocynine (Ni-Pc) is a class of macro-cyclic compounds that has bivalent, tetradentade, planar, and 18 π-conjugated electron aromatic ring systems. Pcs are composed of four pyrrole units linked to four [aza] (—N=C—) groups at the α-carbon of [Pyrrole] unit and they have four aza bridges and four (phenylene) rings. This study aims to synthesize Nickel (II) Phthalocynine. The new synthesized product has been characterized by FT-IR and 1H-NMR spectroscopy. The procedure of this study includes the synthesis of Nickel (II) Phthalocynine (Ni-Pc) by the reaction of (o-cyanobenzamide) with Nickel that was powdered through heating. Different concentrations of Nickel (II) Phthalocynine were studied regarding the effect of antibacterial activity against two species of bacteria Escherichia coli and staphylococcus aureus by using disk-diffusion methods in Mueller–Hinton agar. The results of synthesis of Nickel (II) Phthalocynine shows a good resistance against the selected bacteria with “the minimum inhibitory concentration” (MIC) and “the minimum bactericidal concentration” (MBC) of (Ni-Pc).
Other Latest Articles
- Synthesis, Spectral Analysis, Stability, Antibacterial, and Antioxidant of Fe(II) Mixed Ligands Complex of Imidazole and 1,10-Phenanthroline
- Immunohistochemical Determination of Estrogen and Progesterone Receptors in Women Breast Cancer Patients
- Positive Dimensions of Mental Health and Personality in a Sample of University
- Detection of the Mycotoxin T2 Produced by Fusarium spp. in Some local Cereal Products and Studying Its Phenotypic Characteristics in Baghdad City
- Psychological and Moral Factors for Elderly in Their Adaptation to Surgical Procedures: A Quasi-Experimental Study
Last modified: 2022-10-09 03:06:05