Perspective on Metal-Ligand Coordination Complexes and Improvement of Current Drugs for Neurodegenerative Diseases (NDDs)
Journal: Advanced Journal of Chemistry-Section A (Vol.6, No. 1)Publication Date: 2023-01-01
Authors : Mohd Yusuf; Udeep Chawla; Nizamul Haque Ansari; Munesh Sharma; Mohammad Asif;
Page : 31-49
Keywords : Neurodegenerative Diseases; Metal-ligand complexes; Coordination complexes; Drug; Alzheimer's disease; Parkinson's disease; Prion protein disease;
Abstract
Neurodegenerative diseases (NDDs) associated with the steady loss of neural functionality by the action of irreversible damage or death of neurons are one the most serious diseases amongst human beings. The most common NDDs are including Alzheimer’s disease, Prion protein disease, and Parkinson’s disorder. Several coordination complexes are effective in the treatment of NDDs. In the present scenario, computational methods opened a new vista for novel drugs with theoretically improved overall effectiveness. This review highlights the current trends of computational designs of coordination complexes in developing new drug discovery options and their potential to treat different neurodegenerative diseases with up-to-date R&D exploration with future perspectives.
Other Latest Articles
- (S)-N-(4-Carbamoylphenyl)-8-Cyclopropyl-7-(Naphthalen-1-ylmethyl)-5-Oxo-2,3-Dihydro-5H-Thiazolo[3,2-a]Pyridine-3-Carboxamide, A Better Inhibitor of SARS-Cov-2 Spike Glycoprotein Than Some Standard Drugs: A Computational Prediction
- Production of Methyl Ester from Used Cottonseed Oil Optimized Using Box Behnken Design Approach
- MICROFLORICULTURE SOUVENIR CREATIVE INDUSTRY: FEASIBILITY STUDY
- MICROFLORICULTURE SOUVENIR CREATIVE INDUSTRY: FEASIBILITY STUDY
- PSYCHOSOCIAL COMPONENTS AND BEHAVIORAL EFFECTS ON OCCUPATIONAL HEALTH AND SAFETY OF MINING WORKERS IN NORTH MINAHASA REGENCY, NORTH SULAWESI PROVINCE
Last modified: 2022-12-23 14:33:55