Changes in the Content of Nucleic Acids in Brain Neurons under Various Modes of Low Radiation Exposure |Biomedgrid

Nucleic acids are the most important radiation target of cells. However, despite the huge number of researches on the problem, their dynamics in the brain neurons throughout the entire period of post radiation remains unexplored. In this regard, the aim of this research was to study the state of nucleic acids in the brain neurons of rats after irradiation at doses of 0.1 to 1 Gy over their entire life span. The experiment was performed in compliance with the rules of bioethics on 390 white male mongrel rats at the age of 4 months. by the beginning of the study, weighing 210±10 g, which were irradiated with gamma quanta (Co-60) with an energy of 1.2 MeV once and fractionated (in equal portions for 5 days) at total doses of 0.1; 0.2; 0.5 and 1.0 Gy with a dose rate of 0.5 Gy/h and 0.5 Gy with a dose rate of 0.5; 1.0; 2.5 and 6.6 Gy/h. The animals that were exposed to false irradiation – at the same time as the irradiated ones – served as a control.