Targeting Cancer Through NF-KB Pathway with Selected Natural Products (β-Elemene, Puerarin and Gypenosides) |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.10, No. 1)Publication Date: 2020-08-20
Authors : Bashir Ahmad; Pengyu Su; Syed Rafiq Hussain Shah; Shah Zeb Khan; Badshah Hussain; Fazal Wahid; Hayat Ullah; Shahab Uddin; Manzoor Ahmad; Nasiha Begum;
Page : 50-53
Keywords : Cancer; Natural Products; β-Elemene; Puerarin; Gypenosides;
Abstract
Cancer is the second leading cause of mortality around the world; therefore, its immediate treatment is very necessary. Natural products (NPs) are considered more effective and less toxic among all therapies. The vital sources of these natural products are medicinal plants. Various studies have reported that the NPs cure cancer through modulation of the NF-kB pathway. Among the NPs, β-Elemene (ELE), Puerarin (Pue) and Gypenosides (Pue) possess potent anti-tumor effect via regulation of NF-kB pathway; therefore we summarize the available studies to provide a baseline for further research on these NPs.
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