Anti-oxidant and Anti-free Radical Activities of Natural Oil Blend Formulation: Implication for Immune Regulation and Potential Adjuvant Treatment in Infectious Diseases |Biomedgrid

In the present work, the human peripheral blood polymorphonuclear neutrophils phagocytosis, neutrophils oxidative burst regulation, and anti-free radical activity of Natural Oil Blend (NOB) contained Gardenia jasminoides, Commiphora myrrha, Boswellia serrata, Foeniculum vulgarea and Daucus carota essential oils evaluated. Using quantitative flow cytometry in this study we investigated the influence of NOB on neutrophils phagocytosis, and also on their respiratory burst induction. We demonstrated that NOB enhances human neutrophils phagocytosis but dramatically decreases chemotactic peptide N-formyl-Met-Leu-Phe (fMLP)-, phorbol 12-myristate 13-acetate (PMA)-, and E. coli-induced oxidative burst. Furthermore, the antioxidant activity of NOB confirmed by in vitro studies the anti-free radical scavenging activity.