Radiation-Induced Breast Angiosarcoma After Breast Cancer: A Case Report |Biomedgrid

Radiation-induced breast angiosarcoma is a rare but very aggressive tumor, with high local recurrence rate and poor survival. The approximate incidence of this tumor after radiation therapy (RT) for breast cancer (BC) is 0.1%. The clinical presentation and diagnostic imaging are non-specific; so angiosarcomas are often initially confused with dermatoses attributable to RT, leading to delays in diagnosis. In this article we describe the clinical, radiological and pathological findings of a 76-year-old woman who developed an angiosarcoma two and a half years after RT for BC and died 11 months after this diagnosis. It represents a clinical, radiological and histological challenge. We must always consider and rule out this entity in the face of radioinduced vascular lesions, since early diagnosis and aggressive treatment with free margins are the main prognostic factors.