U.V. Analytical Method Development and Validation of Piroxicam Bulk API

The study was aimed to developed a sensitive ultraviolet (UV) spectrophotometric method for the determination of piroxicam bulk API. The samples and standards were prepared in 0.1M methanolic HCL and the drug was quantified at a lambda max of 333nm using a double beam UV spectrophotometer. The range of linearity for the method was found to be between 2-14 μg/ml, which followed Beer-Lambert's law and the regression coefficient near 1. The validity of the method was extensively tested using statistical parameters such as linearity, range accuracy, precision, LOD and LOQ. The proposed method performed well in terms of mean values and standard deviations. The method was found to be accurate, precise, specific, and fast, making it a reliable way to analyze Piroxicam