The Activity of 2,3-Dimethylquinoxaline against Madurella mycetomatis |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.11, No. 4)Publication Date: 2021-01-05
Authors : Abdelbagi Alfadil; Ahmed Shaker Ali; Hamoud Alsamhan; Huda Alkreathy; Asif Jiman-Fatani; Hind Abdulmajed;
Page : 328-331
Keywords : 2; 3-Dimethylquinoxaline; Eumycetoma; Madurella mycetomatis; Mycetoma; Quinoxaline;
Abstract
Madurella mycetomatis is the most prevalent causative species of the eumycetoma, a chronic progressive neglected tropical disabling infectious disease of the subcutaneous tissue. It carries a significant social and economic burden to the endemic areas. Unfortunately, the available treatment is challenging, requires prolonged therapy, resulting in low cure rates and a high incidence of recurrence. Screening new compounds for antifungal activity against Madurella mycetomatis is needed.
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