Overview on Transdermal Drug Delivery System
Journal: International Journal of Trend in Scientific Research and Development (Vol.7, No. 3)Publication Date: 2023-06-01
Authors : Rajvir Rajpurohit Prashant Khade Deepali Sagar Pratiksha Sarode Ravikiran Sarode;
Page : 660-669
Keywords : Drug Polymer matrix; Permeation enhancers; Backing membrane; Release liner; excipients;
Abstract
The transdermal drug delivery system is a technique that provides drug absorption via the skin. The system has many advantages over conventional administration routes such as intravenous or oral administration for systemic and local drug delivery with simple administration. It is available outside medical institutions, which decreases the burden on patients caused by intravenous administration and decreases loss from the first pass effect of the liver, delivering therapeutic drugs at a controlled ratio. Overcoming the skin barrier, including the stratum corneum and epidermal layer, is necessary to develop transdermal drug formulations. Although chemical and physical enhancers have been developed, they need high doses or high potency to exert efficiency, which induces irritation, causes damage, and reduces the skin barrier function. Mr. Rajvir Rajpurohit | Dr. Prashant Khade | Ms. Deepali Sagar | Ms. Pratiksha Sarode | Mr. Ravikiran Sarode "Overview on: Transdermal Drug Delivery System" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-3 , June 2023, URL: https://www.ijtsrd.com.com/papers/ijtsrd57458.pdf Paper URL: https://www.ijtsrd.com.com/pharmacy/pharmaceutics/57458/overview-on-transdermal-drug-delivery-system/mr-rajvir-rajpurohit
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Last modified: 2023-08-01 21:23:57