Comparison Between the SD BIOLINE Dengue Duo and Two InBios Prototype Dengue Immunochromatographic Tests |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.12, No. 4)Publication Date: 2021-04-08
Authors : Hua-Wei Chen; Tania D. Maldonado; Christina M. Farris; Victor A. Sugiharto; Mark P. Simons; Chonthida Supaprom; Phireak Hip; Maya Williams; Gabriel N. Defang; Calli M. Rooney; Shuenn-Jue L. Wu;
Page : 353-358
Keywords : Dengue Virus; Immunochromatographic Test (ICT); Evaluation; Diagnostic; Rapid Test;
Abstract
Dengue fever, caused by any of the four serotypes of dengue viruses (DENV1-4), is the most important arthropod-borne viral disease in the world. Although dengue diagnostic tests based on polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA) have received the U.S. Food and Drug Administration (FDA) clearance, these assays require specialized equipment and highly trained personnel, and thus not suitable for resource-limited settings. Two immunochromatographic test (ICT) prototypes (traditional and multiplex formats) were recently developed by InBios International Inc. (Seattle, WA) to detect the presence of dengue viral non-structural protein 1 (NS1) antigen or anti-DENV IgG and IgM antibodies in serum.
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