Fecal Microbiota Transplantation (FMT) for the Treatment of Primary Clostridium Difficile-Associated Diarrhea: A Pioneer Case Study in ASEAN |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.12, No. 6)Publication Date: 2021-05-07
Authors : Likhasit Sanglutong; Sarita Ratana-Amornpin; Ratha-korn Vilaichone;
Page : 574-576
Keywords : Clostridium Difficile; Antimicrobial Therapy; Metronidazole; Gastrointestinal Tract Flora; Gut-Bacterial Dysbiosis;
Abstract
Fecal microbiota transplantation (FMT) has been recently introduced in Association of Southeast Asian Nations (ASEAN) to treat many diseases affecting gut-bacterial dysbiosis. Clostridium Difficile infection results from disruption of normal gastrointestinal tract flora. Hence, FMT has been approved to be an alternative treatment of recurrent Clostridium Difficile (C. difficile) infection which reported from many studies with higher curative rate, lower recurrence rate, and lower cost of treatment than antimicrobial therapy. There was only one study reported higher efficacy of FMT for treating primary C. difficile infection and lower recurrence rate compared with metronidazole. This present report is a pioneer case in ASEAN who developed primary C. difficile infection treated with FMT. We report the case of a 51-year-old man was diagnosed with communityacquired pneumonia and admitted to Thammasat University Hospital, Thailand.
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