Liver and Kidney Function Trends in a Population Under Mass Treatment with Ivermectin in The North West Region of Cameroon (Onchocerciasis Endemic Region) |Biomedgrid
Journal: American Journal of Biomedical Science & Research (Vol.13, No. 3)Publication Date: 2021-06-21
Authors : Kanjo Shiynsa F; Kamga FHL; Njunda A L; Tientche B; Jules Clement Assob Nguedia;
Page : 287-294
Keywords : Onchocerciasis; Menchum Valley Subdivision; Ivermectin; Aspartate Aminotransferase; Alanine Aminotransferase;
Abstract
Background: In Cameroon, despite mass administration for more than 16 years of ivermectin, the transmission of onchocerciasis remains persistant. Therefore community-directed treatment with ivermectin continues. Long-term exposure of ivermectin following repeated annual distribution to treat onchocerciasis on the liver and kidney functions could lead to the discontinuity of community Directed Treatment with Ivermectin (CDTI). Insufficient data exist on the liver and kidney function parameters following yearly ivermectin treatment. This study thus reports the liver and kidney functions of individuals who have been receiving ivermectin compared to those not treated in the Menchum Valley of North- West Region Cameroon.
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