The Role of Interferon Beta Administration in COVID-19 Treatment |Biomedgrid

Coronavirus disease 2019 (COVID-19) is still a major challenging pandemic in our century and has become a public health concern. Although many safe COVID-19 vaccines are introduced to the public, new variants of the virus still exist, which make the infection more severe and associated with faster spread. Until now, there is a lack of effective therapeutic options for treatment, so many efforts have been raised to find promising effective agents. Interferons (IFNs) are a group of cytokines produced in response to infections with antiviral and immune-modulating actions. Previous studies revealed IFNs efficacy in Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). It's recommended that early administration of IFN-β (within 7 days from the onset of symptoms) might improve survival rate and clinical response and decrease mortality among COVID-19 patients.