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Reference Interval Limits for Serum Biochemistry Analytes for Adult and Geriatric Population of TaitaTaveta County, Kenya |Biomedgrid

Journal: American Journal of Biomedical Science & Research (Vol.15, No. 2)

Publication Date:

Authors : ; ; ; ;

Page : 187-205

Keywords : Biochemistry; Geriatric population; Diagnosis; Medicines; Medical literature;

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Abstract

There are few reference interval limits established for routine serum biochemistry analytes for geriatrics in Africa and none in Kenya. This cross-sectional prospective study involving healthy 304 adults and geriatrics randomly recruited from Taita-Taveta County, Kenya meeting Clinical and Laboratory Standards Institute guidelines were used to establish median and 95% range reference interval limits for thirteen routine serum biochemistry analytes. This study has developed age and sex specific reference interval limits for some of the thirteen serum biochemistry analytes for adults and geriatrics of Taita-Taveta County, Kenya that differ from those previously reported in literature from different parts of the world including those of Caucasians and Africans. Therefore, continued use of Caucasian population reference interval limits for these serum biochemistry analytes from textbooks and refereed journal articles, instruments manuals and reagents insert, may lead to misdiagnosis and mismanagement of diseases associated with abnormalities of these parameters. The developed reference interval limits for these serum biochemistry analytes may be adopted for use in adults and geriatrics of Taita-Taveta County for effective care and management of patients.

Last modified: 2023-12-12 21:55:41