A REVIEW ON NEW ANTIHYPERTENSIVE AGENT: IRBESARTAN

Hypertension is currently measure disorder obtain in the world population. Irbesartan is classified as an angiotensin II receptor type 1 antagonist. Angiotensin II receptor type 1 antagonists are widely used in treatment of diseases like hypertension, heart failure, myocardial infarction and diabetic nephropathy.The clinical and pharmacological analysis of this drug givesidea about effectivity of this drug in hypertension condition.Irbesartan act on renin angiotensin system and decreases biding of angiotensin to the receptor so decreases the blood pressure and act as an antihyper tensive agent. Irbesartan is tetrazole derivative which selectively inhibit or antagonise the angiotensin type II receptor. In this review gives detail about mechanism of action of irbesartan in hypertension. Keywords: Irbesartan, Hypertension, Anti hypert ensive drug, Angiotensin ii receptor antagonist