Histopathological Changes Associated with Cutaneous Leishmaniasis Patients in Babil Governorate

- The study was performed to evaluate the histological changes in ulcers of infected patients with cutaneous leishmaniasis in Babil governorate/ Iraq. The study was performed in Al-Sadeq hospital, Al-kifil hospital, Musaib hospital and Alexandria hospital within Governorate of Babil from 1/9/2021 to 1/4/2022. In our study we used full thickness biopsy stained with (H&E) and direct smear stained with Geimsa stain technique taken from each ulcer of 22 patients infected with CL. We could identify amastigote stage of the parasite in 8 of 22 patient (36%) by full thickness biopsy and (H&E) stain and in 10 of the 22 (45%) infected patients using direct smear stained with Geimsa stain. We could identify amastigote in one slide in the epidermis which is considered a rare finding. We could identify a heavy inflammatory cell infiltration in the superficial dermis which is considered a diagnostic feature by some authors in the absence of amastigotes in the lesion.