Adverse Drug Reaction (ADR) and Pharmacovigilance: A Current Prospectives
Journal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.8, No. 12)Publication Date: 2023-12-30
Authors : Abhishek Sharma; Aditya Kumar; Akanksha; Ambrish Kumar; Alok Kumar Shukla; Dharna Singh Rajawat;
Page : 36-45
Keywords : Adverse drug reaction; pharmacovigilance; side effects; prevention; management;
Abstract
Unwanted medication response is defined as "a significantly undesirable or harmful reaction; side effects typically indicate a risk from additional management and contact for prevention, special care, a change in the dosage schedule, or withdrawal of the product. Generally, ADR have been divided into two types: Type-A which is dose dependent and predictable on the basis of the pharmacology of the drug. e.g. beta blocker. Type-B which is unpredictable and not dose dependent. e.g. anticonvulsant. The science and activities related to the detection, assessment, understanding and prevention of adverse events or any other drug-related problem" is the definition of pharmacovigilance. Post-marketing surveillance and additional ADR monitoring techniques include prescription event monitoring, digital medical record connection, voluntary reporting by hospitals (such as the UK's Yellow Card System), cohort/case control studies, and personal case reports from physicians. Because preventing or reducing the risk of adverse drug reactions (ADRs) continues to be a challenge in our daily clinical practice, reaching the highest level of possible results from treatments continue to be a top priority for individual clinicians.
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