Various therapies against SARS-CoV-2
Journal: Acta Microbiologica Bulgarica (Vol.39, No. 1)Publication Date: 2023-03-01
Authors : Valsamatzi-Panagiotou A. Traykovska M. Miloshev G.Y. Penchovsky R.;
Page : 3-11
Keywords : SARS-CoV-2; therapies; vaccines; genome organization of SARS-CoV-2;
Abstract
An outbreak of coronavirus SARS-CoV-2 infection in December 2019 in Wuhan, a province of Chi¬na, has caused a worldwide pandemic that led to devastating effects on healthcare systems and the econ¬omy worldwide. The contagiousness of the infection and the consequences of the disease in everyday life highlighted the great need for a suitable treatment against coronavirus as soon as possible. Therefore, lots of scientists all around the world focused on the discovery of a proper therapy against the virus. The pres¬ent article explains the structure of the virus, the pathophysiology of the infection with SARS-CoV-2, and various therapies against SARS-CoV-2. The first data that concern the effectiveness of vaccines from the countries that have already started mass vaccinations are positive. However, it is very early to conclude about the efficacy of vaccines in the population. The appearance of novel virus mutations raises concerns and forces some countries to impose further restrictions. The latest and the most contagious variant, known as Omicron, seems to decrease the global pandemic significantly. New SARS-CoV-2 therapies are suggest¬ed based on antisense technology.
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