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Clinico-morphological рarallels vulgaris and rosacea acne

Journal: Scientific review, Науковий огляд, Научное обозрение (Vol.14, No. 4)

Publication Date:

Authors : ; ; ; ; ;

Page : 83-91

Keywords : vulgaris and rosacea acne; clinic; skin microbiota; reduced tolerance.;

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Vulgaris and rosacea acne are common pathologies of the skin in the structure of dermatology and occupy a significant place among referral of patients as in the institution of preventive medical and aesthetic profile. Peculiarities of localization of these diseases in this category of patients and are fairly frequent and important cause of reduced quality of life, and along with a long period, in many cases resistant to current methods of treatment, leads to the formation of social maladjustment. All this shows the relevance and necessity of learning further investigation vulgaris and rosacea acne, especially issues of etiopathogenesis, which largely remain open to the present time, and clinical features of these diseases that can allow to increase the effectiveness of preventive measures and, consequently, to improve the quality of life of such patients. The purpose of the study was to determine the clinical and morphological features and parallel flow acne vulgaris and rosacea. Under supervision there were 87 patients with acne (59 ? vulgaris, papulopustulosa form; 28 ? rosacea, papulopustulosa stage) with moderate current, aged 18 to 45 years. All the patients underwent clinical and laboratory examination and microbiological ? examination of the microbiota of the skin; statistical data processing was performed using the STATISTICA® for Windows 6.0". The results of our study confirm the existence of similarity of the signs current vulgaris and rosacea acne, this is: localization; the nature of the rash in the area of the skin inflammation (papulopustules morphological elements in the same form and stage vulgaris and rosacea acne, respectively); long duration with the formation of cosmetic flaws; changes in the psychosocial sphere; the common precipitating factors (stress, pathology of the digestive tract), and also change the microbiota of the skin (credible violations of both species and quantitative composition), which can be attributed to a common trigger factors. Thus patients with vulgaris and rosacea acne are parallels not only in clinical course (especially expressed in papular and pustular elements of the rash), but similar changes in the ecosystem of the skin (in the form of increased its degree of contamination and the changes of quantitative and qualitative nature) ? reduced toleranse that creates an abundance of pathogen-associated molecular patterns to activate TLRs and, thus, leads to the formation of a vicious pathological circle.

Last modified: 2015-05-20 20:06:28