A REVIEW: APPLICATION OF NANOPARTICLES IN THE FORM OF TRANSDERMAL PATCHES

The new scientific innovation of engineering nanoparticles (NPs) at the atomic scale (diameter<100nm) has led to numerous novel and useful wide applications in electronics, chemicals, environmental protection, medical imaging, disease diagnoses, drug delivery, cancer treatment, gene therapy, etc. These ultrafine particles are capable of entering the body through skin pores, debilitated tissues, injection, olfactory, respiratory and intestinal tracts. Drug crystallization in transdermal patches is still a major challenge, confronting the formulation development of topical drug delivery systems. In this review, we describe the specific advantages and disadvantages of TDDS, characterization methods, and potential of each method. The influence of using nanoparticles in TDDS has become a topic of interest and is expected to find applications in a wide range of fields.