INNOVATIONS IN MICROEMULSION TECHNOLOGY: A STATE-OF-THE-ART APPROACH FOR TOPICAL DRUG DELIVERY
Journal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.9, No. 6)Publication Date: 2024-06-30
Authors : Rabnoor Alam; Ajay Pratap Singh Chauhan; Harshita Singh; Vijay Kumar;
Page : 1-26
Keywords : Microemulgel; topical delivery; formulation; characterization; drug permeability; stability; applications;
Abstract
A topical drug delivery system usually denotes local dermatological activity as the effect of the pharmaceutical component on the skin to cure the disease. The microemulgel can be used to achieve a combined effect of microemulsion and gel. It shows the dual control release effect of drugs and increasing stability. It has the primary objective ability to incorporate hydrophobic drugs. Various market products containing foreign agent, for example gel, cream, ointment they have several drawbacks, including poor absorption, poor permeability, allergic reaction, irritation, less spreading stickiness, and stability problem. This evaluation provides a summary of the best properties, excipient, preparation, and evaluation related to microemulgel. A recent study of recent development and future directions for microemulgel-based systems was conducted. The emulgel provides various beneficial aspects of its cosmetic and dermatology activity, thixotropic, greaseless, emollient, easily distributed, readily removable, non-staining and water-soluble, with a long half-life, biocompatible, and transparent and pleasant appearing. Therefore, emulgel is a better semi-solid preparation neither conventional system nowadays. It is utilized to administer of anti-inflammatory, anti-fungal, anti-acne, analgesic, anti-psoriasis drugs. The formulated emulgel is characterized of various parameters such as pH, viscosity, spreadability, etc. its need and merit will advance in the upcoming years.
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Last modified: 2024-06-08 16:13:45