An Atypical Presentation of Non-Gestational Choriocarcinoma During the COVID-19 Pandemic: A Case Report |Biomedgrid

Non-gestational choriocarcinoma is a markedly aggressive ovarian germ cell tumor. This report describes an atypical presentation of nongestational choriocarcinoma in a premenopausal female during the COVID-19 pandemic. The patient initially presented with respiratory symptoms and ultimately progressed to multi-organ failure. She underwent an extensive and thorough work up without a diagnosis for many weeks. A pelvic lesion was incidentally noted on routine exam and after histologic evaluation, she was diagnosed with non-gestational choriocarcinoma. The patient expired from respiratory failure secondary to widely metastatic disease within a day of diagnosis and before treatment could be initiated. The aim of this case report is to describe a rare gynecologic malignancy presenting as a diagnostic challenge for gynecologic and non-gynecologic providers alike.