Progress of Anti-Aging Drugs and Their Formulation

Advancements in biotechnology has dramatically improved the screening of anti-aging drugs. A number of drugs have been reported to extend life span based on animal and or human clinical study. Approaches like reverse cellular aging, antioxidant, and various drug's mechanisms are proposed. The success of an anti-aging drug application relies not only on the early stages of drug screening and preclinical studies but also PK/PD prediction prior to the clinical study. In drug dosage design, the oral formulation is still the most commonly needed due to its convenience in administration. In addition, to improve the development of anti-aging oral formulation, an alternative method using FDA approved drugs PK database and PAMPA Dissolution was also proposed for formulation development.