Unveiling the Significance of Stem Cell Therapy for Gastric and Peptic Ulcer Patients

Globally, ulcers are identified as a substantial healthcare burden that requires comprehensive management solutions in order to maximize patient outcomes. Well established treatments, such as antibiotic therapy for the eradication of Helicobacter pylori, mucosal protective medicines, histamine-2 receptor antagonists (H2RAs), and proton pump inhibitors (PPIs) may provide long term side effects as they were used as a long term therapy. In order to minimize the side effects of long term use, complementary methods such as non-pharmacological therapies like lifestyle changes, endoscopic procedures, and surgical options were currently gaining the most prominent attention. In addition, recently stem cell therapy is gaining more attention from the researchers as it has a more significant quality of regeneration. Stem cell therapy is commonly used to repair or replace damaged cells or tissues, but it can also be utilized to prevent damage. Stem cell therapy involves the use of mesenchymal stromal stem cells (BSC) derived from bone marrow and adipose tissue-derived mesenchymal stromal cells (ASC). However, adipose-derived mesenchymal stem cells are easily accessible in large quantities with little invasive intervention. These cells are very flexible and can develop in vitro into a variety of cell types. This review offers a summary of the significance of stem cell therapy in treating gastric ulcer and provides insights in to pros and cons of stem cell therapy in gastric ulcer healing.