Endometrial Microbiome and Development of Gut Microbiota in Foetus

The human microbiota influences physiology, disease, and metabolic reproduction that maintains major function of human physiological properties. Similarly, there has been a debate regarding the endometrial or the uterine microbiota has been one of the major properties of microbiome that influences the physiological development of gut microbiota in foetus. However, origin of microbiome under uterine cavity and placental development has been a question of debate where various assistance suggests on the microbial diffusion and osmosis through the vaginal vaults to the labial commissure. On the contrary, with the detailed study of various clinical aspects and literature justified that the rapid development of microbiome especially with the Lactobacillus Dominant groups covers around 95 of the gut development. Apart from this, previous study suggested reserved from the Human Microbial Project suggested that Normal vaginal delivery led to the growth of Lactobacillus and Bifidobacterium spp., Enterobacteriacea, Bacteriodes fragilis, and 16srRNA based bacteria. On the contrary, the C section found growth of Clostridia, Bacteriodetes Spp., Staphylococcus and Streptococci. Similarly, the full term pregnancy and pre term pregnancy leads to development of different shades of bacteria in the foetal gut. Thus, these review structure as well as the clinical study verified the aspects of various debates regarding the existence of microbiome across the endometrium and surpassing of these throughout the foetal gut in natal development phase. Priyankesh Mishra | Dr. Sinchan Das "Endometrial Microbiome & Development of Gut Microbiota in Foetus" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-8 | Issue-3 , June 2024, URL: https://www.ijtsrd.com/papers/ijtsrd64752.pdf Paper Url: https://www.ijtsrd.com/medicine/gynecology/64752/endometrial-microbiome-and-development-of-gut-microbiota-in-foetus/priyankesh-mishra