STUDY OF COAGULATION PROFILE IN TYPE 2 DIABETES MELLITUS
Journal: International Journal of Advanced Research (Vol.12, No. 09)Publication Date: 2024-09-15
Authors : Bhavana Baladaniya Monika Nanavati; Hansa Goswami;
Page : 246-251
Keywords : Type 2 Diabetes Mellitus Comparative Study Coagulation Profiles Hypercoagulable State;
Abstract
Introduction:Diabetes mellitus is a chronic condition which has high risk for microvascular and macrovascular comorbidities by the process ofbinding of glucose molecules tovariousproteinsinvolvedinthecoagulationmechanism. The current study was carried out to determine the coagulation profiles of type 2 diabetes mellitus patients in comparison with apparently healthy controls. Methods:This was a comparative cross-sectional study carried out atTertiary careteaching institute Ahmedabad. Platelet parameters were determined by using HoribaPentraXLRautomated Hematology analyzer, whereas coagulation analysis was done using ACLTOP300CTSFullyAutomatedCoagulometer. The descriptive and analytical analysis was performed using MicrosoftExcel and SPSS software. We used student t-testtoanalyzethedifferencebetweenthemeans.AP-valuelessthan0.05wasset forthestatisticalsignificancedetermination. Result: The mean PT, INR and APTT in the Diabeticcase group were 11.46±1.63,0.98±1.14and29.83±4.09respectively.Thereweresignificantdifferences (p value<0.05) in the PT, INR and APTT between caseandhealthycontrolgroups.The mean platelet count was 257.92±75.48 and the mean MPV was8.00±1.03. Conclusion: The present study revealed reduced values ofPT,INR,APTT and no significant differences in platelet countsand MPVbetweendiabeticpatients andhealthycontrols.Thus,thefindingissuggestive of hyper- coagulable tendencies of diabetic patients compared to controls.
Other Latest Articles
- FROM SEED TO SHRUB: A THOROUGH REVIEW OF BIXA ORELLANA AND ITS DIVERSE APPLICATIONS
- ILLUMINATING ASTHMA’S COMPLEXITY: UNRAVELING THE MOLECULAR MECHANISM OF BETA-2 RECEPTOR AGONISTDRIVEN BRONCHIAL SMOOTH MUSCLE RELAXATION
- DETERMINATION OF IN VITRO ALPHA AMYLASE INHIBITORY AND ANTIGLYCATION STUDIES OF ROOT AND STEM EXTRACTS OF URENA SINUATA
- MOLECULAR DOCKING STUDIES OF PHYTOCONSTITUENTS IDENTIFIED FROM TRADITIONAL MEDICINAL PLANTS FOR PROTEASE AND REVERSE TRANSCRIPTASE TARGETED ANTI-HIV ACTIVITY
- SYNTHESIS OF SOAP FROM EDIBLE OILS USING A BIO-BASED CATALYST DERIVED FROM MUSA BALBISISANA COLLA AND A COMPARATIVE STUDY OF QUALITY PARAMETERS
Last modified: 2024-10-03 17:59:54