Hepatic biochemical profile in guinea pigs fed with pisonay (Erythrina edulis) meal

Objective. Evaluate the variations of the inclusion of Erythrina edulis leaf meal (EELM) of three regrowth ages (Ra) on the hepatic metabolites of guinea pigs. Materials and methods. 100 improved male guinea pigs assigned to ten diets-treatments were used: (T0) 20% lucerna meal, (T1) 4 Ra/10% EELM, (T2) 4 Ra/20% EELM, (T3) 4 Ra/30% EELM, (T4) 8 Ra/10% EELM, (T5) 8 Ra/20% EELM, (T6) 8 Ra/30% EELM, (T7) 12 Ra/10% EELM, (T8) 12 Ra/20% EELM, (T9) 12 Ra/30% EELM. At 56 days, blood samples in order to determine total protein, albumin, total bilirubin, aminotransferases, alkaline phosphatase, and gamma-glutamyl transpeptidase they collected and were analyzed undering completely randomized design. In addition, was used the factorial arrangement to evaluate the Regrowth Age Factor and the Inclusion Levels Factor. Results. The diets-treatments and the inclusion of EELM did not affect the serum concentration of total protein (p>0.05). The diets-treatments, regrowth age and inclusion did not affect alkaline phosphatase (p>0.05). The inclusion had no effect on albumin and gamma-glutamyl transpeptidase (p>0.05). The concentration of total bilirubin and aminotransferases were affected by the diets-treatments and decreased with increasing age at regrowth and the inclusion of EELM (p<0.05). Albumin and gamma-glutamyl transpeptidase increased due to the effect of regrowth age (p<0.05). Conclusions. The inclusion of EELM from three regrowth ages does not cause variations in hepatic metabolites since they are within acceptable levels for guinea pigs.