FROM GUIDELINES TO MISSED OPPORTUNITIES: A CRITICAL ANALYSIS OF ANCA VASCULITIS MANAGEMENT PRACTICES

Antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) represents a collection of rare autoimmune disorders that primarily target small blood vessels. This group includes granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis (MPA). The diagnosis of AAV is multifaceted, relying on a combination of clinical assessments, biological markers, radiological imaging, and histopathological evaluations.Although the revised Chapel Hill classification has refined disease definitions, the absence of ANCAs in some patients can complicate diagnosis. The management of AAV typically begins with an induction phase aimed at inducing remission.