IMPACT OF MICELLAR CHARACTERISTICS ON THE DISSOLUTION AND EFFICACY OF ANTICANCER AGENTS: A REVIEW
Journal: International Journal of Advanced Research (Vol.13, No. 03)Publication Date: 2025-03-20
Authors : Koushlendra Singh Rajput Ram Krishna Shrivastava; L.K. Tiwary;
Page : 138-145
Keywords : Micellar Characteristics Dissolution Drug Delivery Anticancer Agents Surface Charge;
Abstract
Micellar drug delivery system is one of the potentially efficient approaches for increasing the solubility, stability, and bioavailability of hydrophobic anticancer agents. This review study investigates the effects of major micellar properties on the solubility and therapeutic effectiveness of anticancer medications, including size, shape, surface charge, and stability. The non-spherical micelles may increase cellular uptake and lengthen circulation time, while smaller
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